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Pathogens (bacteria and viruses that cause disease) can enter the body through various passages. Skin provides good protection against entry from pathogens so your vulnerable areas are your eyes, nose, mouth, ears and open wounds. Your (unwashed) hands can deliver pathogens to these areas.
Airborne pathogens will enter through the mouth or nose as you breath them in.
Pathogens in food will enter through your mouth into your digestive system.
Pathogens can also enter through "vectors" directly into the blood stream - through mosquitos, fleas, ticks or contaminated needles, for example.
It is important to remember that the body has many natural defenses to prevent pathogens entering the body, such as blood clotting at wounds, and enzymes in the eyes, nose and mouth that break down harmful bacteria